One Health is the concept that human, animal, and environmental health are intertwined. Collaboration of all relevant sectors is key and the current COVID19 pandemic reassured the need for One Health approach and interdisciplinary when confronting global health challenges. Amoud University is hosting a regional networking conference for the Horn of Africa universities (3rd -5th January 2022) to showcase the current One Health implementation status, research capacity, and creating a future collaborative network to facilitate partnershipbetween researchers and institutions. Representatives from 20 universities, International and local Non-Governmental Organizations, UN agencies, Government and private sector will participate in a three-day networking event in Amoud University, Borama, Somaliland. The conference was sponsored by One Health Regional Network for the Horn of Africa (HORN) and Amoud University.